ARF PROTEINS - THE MEMBRANE TRAFFIC POLICE

被引:232
作者
BOMAN, AL
KAHN, RA
机构
[1] Laboratory of Biological Chemistry, Developmental Therapeutics Program, DCT, Bethesda
关键词
D O I
10.1016/S0968-0004(00)88991-4
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Cofactor for cholera toxin; activator of phospholipase D; regulator of coat-protein assembly; inhibitor of membrane traffic; ability to cause expansion of the endoplasmic reticulum and vesiculation of the Golgi; sensitivity to membrane phospholipids - each of these activities has been attributed to Arf proteins. Can a single molecular mechanism link them all?
引用
收藏
页码:147 / 150
页数:4
相关论文
共 37 条
  • [11] BINDING OF ARF AND BETA-COP TO GOLGI MEMBRANES - POSSIBLE REGULATION BY A TRIMERIC G-PROTEIN
    DONALDSON, JG
    KAHN, RA
    LIPPINCOTTSCHWARTZ, J
    KLAUSNER, RD
    [J]. SCIENCE, 1991, 254 (5035) : 1197 - 1199
  • [12] FRANCO M, 1993, J BIOL CHEM, V268, P24531
  • [13] HANEY SA, 1994, J BIOL CHEM, V269, P16541
  • [14] HAUN RS, 1993, J BIOL CHEM, V268, P7064
  • [15] 2 DISTINCT POPULATIONS OF ARF BOUND TO GOLGI MEMBRANES
    HELMS, JB
    PALMER, DJ
    ROTHMAN, JE
    [J]. JOURNAL OF CELL BIOLOGY, 1993, 121 (04) : 751 - 760
  • [16] G-PROTEINS
    HEPLER, JR
    GILMAN, AG
    [J]. TRENDS IN BIOCHEMICAL SCIENCES, 1992, 17 (10) : 383 - 387
  • [17] HONG JX, 1994, J BIOL CHEM, V269, P9743
  • [18] KAHN RA, 1984, J BIOL CHEM, V259, P6228
  • [19] KAHN RA, 1991, J BIOL CHEM, V266, P15595
  • [20] KAHN RA, 1992, J BIOL CHEM, V267, P13039