SYNTHESIS OF HIGHLY FUNCTIONALIZED 3,4-DIHYDRO-2H-PYRANS BY HIGH-PRESSURE LEWIS-ACID CATALYZED CYCLOADDITION OF ENOL ETHERS AND ALPHA,BETA-UNSATURATED ALDEHYDES

被引：13

作者：

VANDENPUT, DAL ^{[1
]}

SCHEEREN, HW ^{[1
]}

机构：

[1] CATHOLIC UNIV NIJMEGEN,NSR,CTR MOLEC STRUCT DESIGN & SYNTH,DEPT ORGAN CHEM,6525 ED NIJMEGEN,NETHERLANDS

来源：

TETRAHEDRON | 1995年 / 51卷 / 30期

关键词：

D O I：

10.1016/0040-4020(95)00449-I

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

New highly substituted 3,4-dihydro-2H-pyrans were synthesized with high ENDO selectivity by high pressure hetero Diels Alder reactions of alpha,beta-unsaturated aldehydes and enol ethers in the presence of lanthanide-catalysts. Chiral induction was studied using chiral catalysts, a chiral enol ether and a combination of these chiralities.

引用

页码：8383 / 8388

页数：6