学术探索
学术期刊
新闻热点
数据分析
智能评审

THE CROONIAN LECTURE, 1993 - THE ENDOTHELIUM - MAESTRO OF THE BLOOD-CIRCULATION

被引：82
作者：
VANE, JR
机构：
来源：
PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES | 1994年 / 343卷 / 1304期
关键词：
D O I：
10.1098/rstb.1994.0023
中图分类号：
Q [生物科学];
学科分类号：
07 ; 0710 ; 09 ;
摘要：
The vascular endothelium plays a vital role in the control of the circulation. It metabolizes various vasoactive substances, coverts angiotensin I to angiotensin II and secretes the potent vasodilators prostacyclin and EDRF(NO) and the vasoconstrictor peptide endothelin-1. The balance between these mediators determines the responses of the cardiovascular system in diseases such as hypertension, atherosclerosis and myocardial infarction.
引用
收藏
页码：225 / 246
页数：22
相关论文
共 228 条
[1]  
ADELMAN B, 1981, BLOOD, V58, P198
[2]   PREVENTION OF BLOCKAGE OF PARTIALLY OBSTRUCTED CORONARY-ARTERIES WITH PROSTACYCLIN CORRELATES WITH INHIBITION OF PLATELET-AGGREGATION [J].
AIKEN, JW ;
GORMAN, RR ;
SHEBUSKI, RJ .
PROSTAGLANDINS, 1979, 17 (04) :483-494
[3]  
ANGGARD E, 1989, J CARDIOVASC PHARM, V13, pS46
[4]  
ANGGARD E, 1965, J BIOL CHEM, V240, P3515
[5]   CLONING AND EXPRESSION OF A CDNA-ENCODING AN ENDOTHELIN RECEPTOR [J].
ARAI, H ;
HORI, S ;
ARAMORI, I ;
OHKUBO, H ;
NAKANISHI, S .
NATURE, 1990, 348 (6303) :730-732
[6]   CYTOPROTECTIVE ACTIONS OF PROSTACYCLIN DURING HYPOXIA IN THE ISOLATED PERFUSED CAT LIVER [J].
ARAKI, H ;
LEFER, AM .
AMERICAN JOURNAL OF PHYSIOLOGY, 1980, 238 (02) :H176-H181
[7]   CIRCULATING LEVELS OF ENDOTHELIN IN CIRRHOSIS [J].
ASBERT, M ;
GINES, A ;
GINES, P ;
JIMENEZ, W ;
CLARIA, J ;
SALO, J ;
ARROYO, V ;
RIVERA, F ;
RODES, J .
GASTROENTEROLOGY, 1993, 104 (05) :1485-1491
[8]   PROSTACYCLIN PRODUCTION BY ISOLATED ADIPOCYTES [J].
AXELROD, L ;
LEVINE, L .
DIABETES, 1981, 30 (02) :163-167
[9]   ENDOTHELIUM-DEPENDENT INHIBITION OF PLATELET-AGGREGATION [J].
AZUMA, H ;
ISHIKAWA, M ;
SEKIZAKI, S .
BRITISH JOURNAL OF PHARMACOLOGY, 1986, 88 (02) :411-415
[10]   INHIBITION OF ANGIOTENSIN I CONVERTING ENZYME BY VENOM PEPTIDES [J].
BAKHLE, YS .
BRITISH JOURNAL OF PHARMACOLOGY, 1971, 43 (01) :252-&
12345678910