HUMAN MODELS OF MELANOMA

被引：9

作者：

WEINSTOCK, MA

机构：

[1] Dermatoepidemiology Unit, VA Medical Center, Roger Williams Medical Center, Providence, RI

来源：

CLINICS IN DERMATOLOGY | 1992年 / 10卷 / 01期

关键词：

D O I：

10.1016/0738-081X(92)90062-4

中图分类号：

R75 [皮肤病学与性病学];

学科分类号：

100206 ;

摘要：

A human model for melanoma is a circumstance in which melanoma is particularly common. We can use models to gain an understanding of melanoma in two ways: (1) by studying the differences between the model and general susceptible population, we can link those differences to the etiology and pathogenesis of melanoma; (2) by studying differences in melanoma susceptibility among individuals in the model circumstances, we may be able to identify more readily etiologic factors and mechanisms. This article considers the potential of immunosuppression, xeroderma pigmentosum, albinism, psoralen photochemotherapy (PUVA), and artificial high-dose ultraviolet radiation exposures to serve as models for melanoma. Familial melanoma, another model, is discussed by Bergman and Fusaro elsewhere in this issue. © 1992.

引用

页码：83 / 89

页数：7

共 77 条

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