RESULTS OF BIOPSY AFTER EARLY STAGE PROSTATIC-CANCER TREATMENT BY IMPLANTATION OF I125 SEEDS

被引：47

作者：

LYTTON, B ^{[1
]}

COLLINS, JT ^{[1
]}

WEISS, RM ^{[1
]}

SCHIFF, M ^{[1
]}

MCGUIRE, EJ ^{[1
]}

LIVOLSI, V ^{[1
]}

机构：

[1] YALE UNIV,SCH MED,DEPT THERAPEUT RADIOL & PATHOL,NEW HAVEN,CT 06520

来源：

JOURNAL OF UROLOGY | 1979年 / 121卷 / 03期

关键词：

D O I：

10.1016/S0022-5347(17)56764-6

中图分类号：

R5 [内科学]; R69 [泌尿科学（泌尿生殖系疾病）];

学科分类号：

1002 ; 100201 ;

摘要：

We have treated 77 patients for clinically early stage carcinoma of the prostate, 9 stage A2, 63 stage B and 5 stage C, with direct implantation of 125I seeds into the prostate and pelvic lymphadenectomy. It is estimated that a minimum dose of 15,0n 3 cases a second biopsy was performed after 2 to 3 years. Persistent tumor was present in 11 biopsies. Cytological changes were observed in 8 of these, primarily cytoplasmic vacuolation and nuclear pyknosis. There seemed to be no relationship between grade and stage of disease and histological evidence of persistence of tumor after radiation. One patient with persistent tumor asis. The remaining 10 patients with persistent tumor have shown no sign of progression of disease during 2 to 4-year interval.

引用

页码：306 / 309

页数：4