CHIRAL 2-ALKYLBRANCHED ACIDS, ESTERS AND ALCOHOLS - PREPARATION AND STEREOSPECIFIC FLAVOR EVALUATION

被引：36

作者：

RETTINGER, K

BURSCHKA, C

SCHEEBEN, P

FUCHS, H

MOSANDL, A

机构：

[1] UNIV FRANKFURT,INST LEBENSMITTELCHEM,ROBERT MAYER STR 7-9,W-6000 FRANKFURT,GERMANY

[2] UNIV WURZBURG,INST ANORGAN CHEM,W-8700 WURZBURG,GERMANY

来源：

TETRAHEDRON-ASYMMETRY | 1991年 / 2卷 / 10期

关键词：

2-ALKYLBRANCHED ACIDS; ESTERS AND ALCOHOLS; FLAVOR SUBSTANCES; CHIRALITY AND ODOR;

D O I：

10.1016/S0957-4166(00)86137-6

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

Racemic 2-alkylbranched acids are transformed to disatereomeric derivatives with (S)-2-hydroxy-3-phenylpropionic acid-N-methylamide or (S)-(-)-1-phenylethylamine and separated by liquid chromatography to pure diastereoisomers, which are subsequently hydrolyzed to yield optically pure acids. Enantiomeric alcohols are generated by LiAlH4-reduction of the corresponding acids, esters are synthesized by different methods. The odour impression of the enantiomeric compounds is investigated.

引用

页码：965 / 968

页数：4

共 13 条

[1] LIPASE-CATALYZED ENANTIOSELECTIVE ESTERIFICATION OF 2-METHYLALKANOIC ACIDS [J].