CONCISE SYNTHETIC ROUTE TO BOTH ENANTIOMERIC FORMS OF 2,3,4,4A-TETRAHYDRO[1,3]DIOXOLO[4,5-J]PHENANTHRIDIN-6(5H)-ONE, THE TETRACYCLIC SKELETON ASSOCIATED WITH THE NARCISSUS ALKALOIDS LYCORICIDINE AND NARCICLASINE

被引：25

作者：

BANWELL, MG ^{[1
]}

COWDEN, CJ ^{[1
]}

MACKAY, MF ^{[1
]}

机构：

[1] LA TROBE UNIV,DEPT CHEM,BUNDOORA,VIC 3083,AUSTRALIA

来源：

JOURNAL OF THE CHEMICAL SOCIETY-CHEMICAL COMMUNICATIONS | 1994年 / 01期

关键词：

D O I：

10.1039/c39940000061

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Both enantiomeric forms, (S)-4 and (R)-4, of the tetracyclic skeleton associated with the title alkaloids 1 and 2 have been prepared; the key step involved silver isocyanate-promoted ring-opening of gem-dibromocyclopropane 5 and trapping of the resulting allylic isocyanate (+/-)-6 with (-)-menthol.

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页码：61 / 62

页数：2

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