A FRACTAL ANALYSIS OF CULTURED RAT OPTIC-NERVE GLIAL GROWTH AND DIFFERENTIATION

被引：47

作者：

SMITH, TG

BEHAR, TN

LANGE, GD

MARKS, WB

SHERIFF, WH

机构：

[1] NINCDS, INSTRUMENTAT & COMP SECT, BETHESDA, MD 20892 USA

[2] NINCDS, NEURAL CONTROL LAB, BETHESDA, MD 20892 USA

来源：

NEUROSCIENCE | 1991年 / 41卷 / 01期

关键词：

D O I：

10.1016/0306-4522(91)90206-4

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

Fractal dimension can be used as a quantitative measure of morphological complexity. Separate, enriched populations of oligodendrocytes or type 2 astrocytes derived from neonatal rat optic nerves were allowed to differentiate in vitro. Fractal dimensions of differentiating glial cells were measured over time. The fractal dimension correlated with perceived complexity and increased in value as the glial cells matured. Analysis of the changes in fractal dimension with time revealed unique rates of growth and differentiation for each glial phenotype.

引用

页码：159 / 166

页数：8

共 33 条

[21] PLATELET-DERIVED GROWTH-FACTOR PROMOTES DIVISION AND MOTILITY AND INHIBITS PREMATURE DIFFERENTIATION OF THE OLIGODENDROCYTE TYPE-2 ASTROCYTE PROGENITOR-CELL [J].