THE SYNTHESIS OF A KEY INTERMEDIATE OF TRICYCLIC BETA-LACTAM ANTIBIOTICS

被引:35
作者
BISMARA, C [1 ]
DIFABIO, R [1 ]
DONATI, D [1 ]
ROSSI, T [1 ]
THOMAS, RJ [1 ]
机构
[1] GLAXO SPA,GLAXO RES LABS,I-37135 VERONA,ITALY
关键词
D O I
10.1016/0040-4039(95)00740-4
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
By employing an intramolecular Sakurai-type olefination it was possible to obtain the olefin 5, a key intermediate in the synthesis of the broad spectrum tricyclic beta-lactam antibiotic GG-326 1.
引用
收藏
页码:4283 / 4286
页数:4
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