PURIFICATION OF HUMAN FACTOR X AND COMPARISON OF PEPTIDE MAPS OF HUMAN FACTOR X AND PROTHROMBIN

被引：46

作者：

ARONSON, DL

MUSTAFA, AJ

MUSHINSKI, JF

机构：

[1] Division of Biologics Standards, National Cancer Institute, National Institutes of Health, Bethesda

来源：

BIOCHIMICA ET BIOPHYSICA ACTA | 1969年 / 188卷 / 01期

基金：

美国国家卫生研究院;

关键词：

D O I：

10.1016/0005-2795(69)90041-5

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Human prothrombin and Factor X have been purified utilizing chromatography on hydroxyapatite. The Factor X has been further purified by preparative disc electrophoresis and DEAE-cellulose chromatography. Comparison of the peptide maps made from tryptic digests shows only about one third of the peptides to be common to the two molecules. These findings indicate that Factor X is not a derivative of prothrombin (nor vice versa). © 1969.

引用

页码：25 / +

页数：1

共 22 条

[1] CHROMATOGRAPHIC DIFFERENTIATION OF HUMAN PROTHROMBINS [J].