ADDITION OF FUNCTIONALIZED ZINC COPPER REAGENTS TO ACETYLENIC ESTERS - SYNTHESIS OF 2-CARBOALKOXY CYCLOHEXENONES

被引：9

作者：

CRIMMINS, MT

HUANG, SJ

GUISE, LE

LACY, DB

机构：

[1] Venable and Kenan Laboratories, Chemistry University of North Carolina at Chapel Hill, Chapel Hill

来源：

TETRAHEDRON LETTERS | 1995年 / 36卷 / 39期

关键词：

FUNCTIONALIZED ZINC REAGENTS; CARBOALKOXYCYCLOHEXENONES; HOMOENOLATES;

D O I：

10.1016/0040-4039(95)01485-Z

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Conjugate addition of the zinc-copper reagent derived from ethyl 4-iodobutyrate to acetylenic esters in the presence of TMSCI and HMPA results in cyclization and formation of 3-alkyl-2-carboalkoxycyclohexenones in good yields.

引用

页码：7061 / 7064

页数：4

共 16 条

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[16] 1,4-ADDITIONS OF THE HIGHLY FUNCTIONALIZED COPPER REAGENTS RCU(CN)ZNI.2 BF3 TO TRISUBSTITUTED ENONES - A NEW BF3 PROMOTED CYCLIZATION REACTION
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