ENANTIOSELECTIVE SYNTHESIS OF ALPHA-METHYL-ALPHA-AMINOCARBOXYLIC ACIDS BY ALKYLATION OF THE LACTIM ETHER OF CYCLO-(L-ALA-L-ALA)

被引：72

作者：

SCHOLLKOPF, U

HARTWIG, W

GROTH, U

机构：

[1] Organisch-Chemisches Institut der Universität, Göttingen, D-3400

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION IN ENGLISH | 1979年 / 18卷 / 11期

关键词：

D O I：

10.1002/anie.197908631

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Preparatively valuable asymmetric amino acid syntheses must be simple to carry out, give yields of >90%, and, where appropriate, permit recovery of the chiral auxiliary agent. These demands are met by the new synthesis via cyclo‐(L‐Ala‐L‐Ala). (Figure Presented.) Copyright © 1979 by Verlag Chemie, GmbH, Germany

引用

页码：863 / 864

页数：2

共 9 条

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[6] ASYMMETRIC SYNTHESIS VIA HETEROCYCLIC INTERMEDIATES .1. ASYMMETRIC SYNTHESIS OF ALPHA-ALKYL-ALPHA-AMINOCARBOXYLIC ACIDS BY ALKYLATION OF 1-CHIRAL-SUBSTITUTED 2-IMIDAZOLIN-5-ONES
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[7] SCHOLLKOPF U, 1978, ANGEW CHEM, V90, P136
[8] ASYMMETRIC SYNTHESIS .2. EXTERNAL ASYMMETRIC STRECKER SYNTHESIS OF ALPHA-METHYL-AMINOACIDS
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[9] ASYMMETRIC SYNTHESES .4. ASYMMETRIC STRECKER SYNTHESIS WITH (S)-(-)-1-PHENYLETHYLAMINE AS CHIRAL HANDLE
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GRIES, K
STEMMLE, B
SCHRANK, W
[J]. CHEMISCHE BERICHTE-RECUEIL, 1977, 110 (06): : 2098 - 2105

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