CHIRAL 2-CYANO ESTERS AS SYNTHETIC INTERMEDIATES IN THE SYNTHESIS OF R-ALPHA-METHYLVALINE AND S-ALPHA-METHYLVALINE

被引：30

作者：

CATIVIELA, C

DIAZDEVILLEGAS, MD

GALVEZ, JA

LAPENA, Y

机构：

[1] Departamento de Química Orgánica. Instituto de Ciencia de Materiales, Aragón. Universidad de Zaragoza-C.S.I.C.

来源：

TETRAHEDRON | 1995年 / 51卷 / 20期

关键词：

D O I：

10.1016/0040-4020(95)00260-F

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A divergent stereoselective synthesis of R and S alpha-methylvaline from (2RS) (1S,2R,4R)-10-dicyclohexylsulfamoylisobornyl 2-cyano-3-methylbutanoate has been developed.

引用

页码：5921 / 5928

页数：8

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