SYNTHESIS OF (R)-2-AMINO-2-METHYLBUTANOIC ACID AND (S)-2-AMINO-2-METHYLBUTANOIC ACID (IVA) IN ENANTIOMERICALLY PURE FORM

被引：15

作者：

CATIVIELA, C

DIAZDEVILLEGAS, MD

GALVEZ, JA

机构：

[1] Instituto de Ciencia de Materiales de Aragón, Departamento de Química Orgánica, Universidad de Zaragoza-C.S.I.C.

来源：

TETRAHEDRON-ASYMMETRY | 1993年 / 4卷 / 07期

关键词：

D O I：

10.1016/S0957-4166(00)80337-7

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

A new strategy for the preparation of both enantiomers of 2-amino-2-methylbutanoic acid (Iva) based on diastereoselective alkylation of (1S,2R,4R)-10-dicyclohexylsulfamoylisobornyl 2-cyanoesters and the corresponding degradation process is described.

引用

页码：1445 / 1448

页数：4

共 14 条

[1] CONFORMATIONAL STUDIES ON PEPTIDES CONTAINING ENANTIOMERIC ALPHA-METHYL ALPHA-AMINO-ACIDS .1. DIFFERENTIAL CONFORMATIONAL PROPERTIES OF (R)-2-METHYLASPARTIC AND (S)-2-METHYLASPARTIC ACID
ALTMANN, KH
ALTMANN, E
MUTTER, M
[J]. HELVETICA CHIMICA ACTA, 1992, 75 (04) : 1198 - 1210
[2] OPTICAL ENANTIOMORPHS OF ISOVALINE
BAKER, CG
FU, SCJ
BIRNBAUM, SM
SOBER, HA
GREENSTEIN, JP
[J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1952, 74 (18) : 4701 - 4702
[3] BALDWIN JE, 1992, SYNLETT, P249
[4] SYNTHESIS OF (R)-3-ALKYL-3-BENZYL-2-AZETIDINONES IN ENANTIOMERICALLY PURE FORM
CATIVIELA, C
DIAZDEVILLEGAS, MD
GALVEZ, JA
[J]. TETRAHEDRON-ASYMMETRY, 1993, 4 (02) : 229 - 238
[5] SYNTHESIS OF (R)-3-BENZYL-3-METHYL-2-AZETIDINONE AND (S)-3-BENZYL-3-METHYL-2-AZETIDINONE IN ENANTIOMERICALLY PURE FORM
CATIVIELA, C
DIAZDEVILLEGAS, MD
GALVEZ, JA
[J]. TETRAHEDRON-ASYMMETRY, 1992, 3 (09) : 1141 - 1144
[6] CHIRAL 2-CYANOCINNAMATES IN CONJUGATE ADDITION ASYMMETRIC ENOLATE TRAPPING REACTIONS
CATIVIELA, C
DIAZDEVILLEGAS, MD
GALVEZ, JA
[J]. BULLETIN OF THE CHEMICAL SOCIETY OF JAPAN, 1992, 65 (06) : 1657 - 1661
[7] Ehrlich F, 1908, BIOCHEM Z, V8, P438
[8] Jung G., 1981, STRUCTURE ACTIVITY N, P75
[9] STRUCTURAL CHARACTERISTICS OF ALPHA-HELICAL PEPTIDE MOLECULES CONTAINING AIB RESIDUES
KARLE, IL
BALARAM, P
[J]. BIOCHEMISTRY, 1990, 29 (29) : 6747 - 6756
[10] THE CONSTRUCTION OF NEW PROTEINS AND ENZYMES - A PROSPECT FOR THE FUTURE
MUTTER, M
[J]. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION IN ENGLISH, 1985, 24 (08): : 639 - 653

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