SYNTHESIS OF (R)-3-BENZYL-3-METHYL-2-AZETIDINONE AND (S)-3-BENZYL-3-METHYL-2-AZETIDINONE IN ENANTIOMERICALLY PURE FORM

被引：6

作者：

CATIVIELA, C

DIAZDEVILLEGAS, MD

GALVEZ, JA

机构：

[1] Instituto de Ciencia de Materiales de Aragón, Departamento de Quimica Orgánica, Universidad de Zaragoza-C.S.I.C.

来源：

TETRAHEDRON-ASYMMETRY | 1992年 / 3卷 / 09期

关键词：

D O I：

10.1016/S0957-4166(00)82097-2

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

The diastereoselective methylation of the enolate of 10-dicyclohexylsulfamoylisobornyl-3-phenyl-2-cyanopropanoate is reported. This methylation was carried out under a variety of conditions to achieve a good yield and selectivity and the reaction product was reduced and cyclised to the corresponding beta-lactam in high yield.

引用

页码：1141 / 1144

页数：4

共 25 条

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