BEHAVIORAL SEQUELAE IN YOUNG-RATS OF ACUTE INTERMITTENT ANTENATAL HYPOXIA

被引：86

作者：

HERMANS, RHM

HUNTER, DE

MCGIVERN, RF

CAIN, CD

LONGO, LD

机构：

[1] LOMA LINDA UNIV, SCH MED, DEPT PHYSIOL, DIV PERINATAL BIOL, LOMA LINDA, CA 92350 USA

[2] LOMA LINDA UNIV, SCH MED, DEPT OBSTET & GYNECOL, LOMA LINDA, CA 92350 USA

[3] SAN DIEGO STATE UNIV, DEPT PSYCHOL, SAN DIEGO, CA 92115 USA

[4] LOMA LINDA UNIV, JL PETTIS VET ADM HOSP, NEUROBIOL RES GRP, LOMA LINDA, CA 92350 USA

[5] LOMA LINDA UNIV, DEPT BIOCHEM, LOMA LINDA, CA 92350 USA

来源：

NEUROTOXICOLOGY AND TERATOLOGY | 1992年 / 14卷 / 02期

关键词：

FETUS; HYPOXIA; PRENATAL; NEUROCHEMISTRY; ORNITHINE DECARBOXYLASE; POLYAMINES; BEHAVIOR;

D O I：

10.1016/0892-0362(92)90060-N

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

Several studies have examined behavioral sequelae of acute or chronic pre- or postnatal hypoxia. However, few of these tested a large battery of behavioral functions, particularly those following relatively mild, intermittent hypoxia. Also, in few studies were the hypoxic pups cross-fostered or the experimenter blinded as to experimental group. In addition, in almost no studies were concomitant hypoxic-induced brain biochemicals measured. The present study tested the hypotheses that mild, intermittent antenatal hypoxia can lead to long-term alterations in neurobehavioral development, as well as neurochemical changes.

引用

页码：119 / 129

页数：11

共 53 条

[1] EFFECTS ON THE OFFSPRING OF CHRONIC LOW EXPOSURE CARBON-MONOXIDE DURING MICE PREGNANCY [J].