REINFORCED UNCROSSLINKED POLY (VINYL ALCOHOL) GELS PRODUCED BY CYCLIC FREEZING-THAWING PROCESSES - A SHORT REVIEW

被引：243

作者：

PEPPAS, NA

STAUFFER, SR

机构：

[1] School of Chemical Engineering, Purdue University, West Lafayette, IN

来源：

JOURNAL OF CONTROLLED RELEASE | 1991年 / 16卷 / 03期

关键词：

POLY (VINYL ALCOHOL); HYDROGEL; BIOMATERIAL; FREEZING OF SOLUTION; SUPERMOLECULAR STRUCTURE;

D O I：

10.1016/0168-3659(91)90007-Z

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Novel methods of preparation of strong poly(vinyl alcohol) hydrogels without utilization of chemical crosslinking or reinforcing agents are reviewed. Aqueous poly (vinyl alcohol) solutions exposed to several freezing-thawing cycles lead to such materials. The process of reinforcement of these hydrogels is a densification of the macromolecular structure. This is probably due to the microparticle-microgel formation within the hydrogel or to microcrystalline structural formations or to partial phase separation. The densification process is more prominent for gels that are exposed to up to five freezing-thawing cycles. Important biomedical and pharmaceutical applications of these gels are reviewed.

引用

页码：305 / 310

页数：6

共 28 条

[21]

Hatakeyema, Yamauchi, Hatakeyema, Effect of thermal hysteresis on structural change of water restrained in poly(vinyl alcohol) pseudo-gel, European Polymer Journal, 23, pp. 361-365, (1987)

[22]

Tamura, Nakamura, Okada, New hydrogel from poly(vinyl alcohol) and its fundamental study for medical applications, Jpn. J. Artif. Organs, 13, pp. 1197-1201, (1984)

[23]

Kuriaki, Nakamura, Mizutani, Application of transparent poly(vinyl alcohol) gel to contact lens, Kobunshi Ronbunshu, 46, pp. 739-743, (1989)

[24]

Tazaki, Kida, Homma, Separation of waterethanol mixture by pervaporation through gel membranes of poly(vinyl alcohol) prepared by freezing and thawing method, Kobunshi Ronbunshu, 46, pp. 733-738, (1989)

[25]

Takamura, Arai, Ishii, Drug release from freeze-thaw poly(vinyl alcohol) gel, Yakugaku Zasshi, 107, pp. 233-237, (1987)

[26]

Katayama, New developments in gel science, Yakugaku Zasshi, 106, pp. 1069-1083, (1986)

[27]

Shiga, Hirose, Okada, Kurauchi, Bending of high strength polymer gel in an electric field, Polym. Prepr., 30, 1, pp. 310-311, (1989)

[28]

Shiga, Hirose, Okada, Kurauchi, Bending of high strength polymer gel in an electric field, Kobunshi Ronbunshu, 46, pp. 709-713, (1989)

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