DEVELOPMENT OF A LABORATORY ROBOTIC SYSTEM FOR AUTOMATED BIOANALYTICAL METHODS .2. A ROBOT COMPUTER-PROGRAM FOR GUARDING TOTALLY AUTOMATED BIOANALYTICAL METHODS

被引:3
作者
WIELING, J [1 ]
HEMPENIUS, J [1 ]
JEURING, HJ [1 ]
JONKMAN, JHG [1 ]
COENEGRACHT, PMJ [1 ]
DOORNBOS, DA [1 ]
机构
[1] UNIV GRONINGEN,DEPT ANALYT CHEM & TOXICOL,CHEMOMETR RES GRP,9713 AW GRONINGEN,NETHERLANDS
关键词
guarding routine for chromatographic malfunctioning and liquid dispensing trouble; HPLC; robot control program; Robotic sample preparation;
D O I
10.1016/0731-7085(90)80083-2
中图分类号
O65 [分析化学];
学科分类号
070302 ; 081704 ;
摘要
The application of fully automated, unattended sample preparation performed by a laboratory robot for the analysis of drugs in biological samples requires the prevention of system failures which may arise in the on-line coupled chromatographic system or in other components of the robotic system. A computer program has been developed which can help to detect such problems. The control program for the robotic sample preparation contains a number of safety measures to intercept robotic or human errors. A routine is implemented, guarding for chromatographic malfunctions and errors in dispensing liquids by the robot. After detection of trouble, sample preparation is interrupted. © 1990.
引用
收藏
页码:577 / 582
页数:6
相关论文
共 2 条
[1]  
HALLORAN K, 1986, LG GC, V4, P1020
[2]   DEVELOPMENT OF A LABORATORY ROBOTIC SYSTEM FOR AUTOMATED BIOANALYTICAL METHODS .1. THE DETERMINATION OF THEOPHYLLINE IN HUMAN PLASMA - A COMPARISON BETWEEN THE ROBOTIZED AND MANUAL METHOD [J].
HEMPENIUS, J ;
WIELING, J ;
JONKMAN, JHG ;
DENOORD, OE ;
COENEGRACHT, PMJ ;
DOORNBOS, DA .
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 1990, 8 (04) :313-320