MATERNAL AND CONGENITAL RUBELLA BEFORE 1964 - FREQUENCY CLINICAL FEATURES AND SEARCH FOR ISOIMMUNE PHENOMENA

被引：12

作者：

WHITE, LR

SEVER, JL

ALEPA, FP

机构：

[1] National Institute of Child Health and Human Development, Bethesda, MD

[2] Section on Infectious Diseases, the Perinatal Research Branch, National Institute of Neurological Diseases and Blindness, Bethesda, MD

来源：

JOURNAL OF PEDIATRICS | 1969年 / 74卷 / 02期

关键词：

D O I：

10.1016/S0022-3476(69)80067-3

中图分类号：

R72 [儿科学];

学科分类号：

100202 ;

摘要：

Maternal rubella occurring during 1959 to 1964 was identified in 25 of 30,059 pregnancies, an attack rate of 4 to 8 per 10,000 pregnancies during this nonepidemic period. The expanded congenital rubella syndrome occurred in infants of these mothers, suggesting that no recent change has occurred in the syndrome or in the virulence of the virus. Increased amounts of anti-IgG antibodies were found in postpartum maternal sera. These anti-immunoglobulins are 19S and probably have no effect on the immunologic competence of the fetus and infant. Cord serum IgM levels were elevated in 3 of 9 patients tested. © 1969 The C. V. Mosby Company.

引用

页码：198 / &

共 26 条

[11] PERSISTENCE OF ALTERED EXPRESSION OF ALLELIC GAMMAG-IMMUNOGLOBULIN ALLOTYPES IN AN ALLOTYPE SUPPRESSED RABBIT AFTER IMMUNIZATION [J].