HIGH-DOSE TAMOXIFEN IN THE TREATMENT OF RECURRENT HIGH-GRADE GLIOMA - A REPORT OF CLINICAL STABILIZATION AND TUMOR-REGRESSION

被引：51

作者：

BALTUCH, G

SHENOUDA, G

LANGLEBEN, A

VILLEMURE, JG

机构：

[1] MCGILL UNIV, DEPT NEUROL & NEUROSURG, MONTREAL H3A 2T5, QUEBEC, CANADA

[2] MCGILL UNIV, DEPT RADIAT ONCOL, MONTREAL H3A 2T5, QUEBEC, CANADA

[3] MCGILL UNIV, DEPT ONCOL, MONTREAL H3A 2T5, QUEBEC, CANADA

来源：

CANADIAN JOURNAL OF NEUROLOGICAL SCIENCES | 1993年 / 20卷 / 02期

关键词：

D O I：

10.1017/S0317167100047788

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

We present a case of recurrent glioma, previously treated with maximal surgery and radiation in which a high dose of tamoxifen has stabilized the tumour clinically and has resulted in it's radiologic regression. Given tamoxifen's relative lack of toxicity, it might serve as a useful adjuvant in the treatment of recurrent glioma.

引用

页码：168 / 170

页数：3

共 22 条

[11] INHIBITION OF PROTEIN-KINASE-C MEDIATED SIGNAL TRANSDUCTION BY TAMOXIFEN - IMPORTANCE FOR ANTITUMOR-ACTIVITY
HORGAN, K
COOKE, E
HALLETT, MB
MANSEL, RE
[J]. BIOCHEMICAL PHARMACOLOGY, 1986, 35 (24) : 4463 - 4465
[12] EVIDENCE THAT TRANSFORMING GROWTH-FACTOR-BETA IS A HORMONALLY REGULATED NEGATIVE GROWTH-FACTOR IN HUMAN-BREAST CANCER-CELLS
KNABBE, C
LIPPMAN, ME
WAKEFIELD, LM
FLANDERS, KC
KASID, A
DERYNCK, R
DICKSON, RB
[J]. CELL, 1987, 48 (03) : 417 - 428
[13] TAMOXIFEN IN THE TREATMENT OF BREAST-CANCER
LEGHA, SS
[J]. ANNALS OF INTERNAL MEDICINE, 1988, 109 (03) : 219 - 228
[14] INTRACAROTID CISPLATIN CHEMOTHERAPY FOR RECURRENT GLIOMAS
MAHALEY, MS
HIPP, SW
DROPCHO, EJ
BERTSCH, L
CUSH, S
TIREY, T
GILLESPIE, GY
[J]. JOURNAL OF NEUROSURGERY, 1989, 70 (03) : 371 - 378
[15] OBRIAN CA, 1985, CANCER RES, V45, P2462
[16] POLLACK IF, 1990, CANCER RES, V50, P7134
[17] ROWLANDS MG, 1990, BIOCHEM PHARMACOL, V49, P283
[18] SU HD, 1985, BIOCHEM PHARMACOL, V34, P3649
[19] HIGH-AFFINITY ANTI-ESTROGEN BINDING-SITE DISTINCT FROM THE ESTROGEN-RECEPTOR
SUTHERLAND, RL
MURPHY, LC
FOO, MS
GREEN, MD
WHYBOURNE, AM
[J]. NATURE, 1980, 288 (5788) : 273 - 275
[20] TRUMP DL, 1991, P AN M AM SOC CLIN, V10, P96

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