URTICARIA-PIGMENTOSA - A REVIEW OF 67 PEDIATRIC CASES

被引：96

作者：

AZANA, JM ^{[1
]}

TORRELO, A ^{[1
]}

MEDIERO, IG ^{[1
]}

ZAMBRANO, A ^{[1
]}

机构：

[1] HOSP NINO JESUS,DEPT PEDIAT DERMATOL,MENENDEZ PELAYO 65,E-28009 MADRID,SPAIN

来源：

PEDIATRIC DERMATOLOGY | 1994年 / 11卷 / 02期

关键词：

D O I：

10.1111/j.1525-1470.1994.tb00560.x

中图分类号：

R75 [皮肤病学与性病学];

学科分类号：

100206 ;

摘要：

Mastocytosis is a disorder of mast cell proliferation that may appear during infancy, childhood, or adulthood. We studied 67 consecutive patients (33 males, 34 females) with urticaria pigmentosa and assessed them fully to determine the presence of systemic involvement. Ages at onset of lesions ranged from birth to 11 years, with most developing in the first year of life. Pruritus was the primary symptom. Hematologic and serum chemistry profile, radiologic skeletal surveys, and bone marrow aspirations were performed. Slight anemia was present in three patients. Radiologic bone lesions were observed in eight. Bone marrow aspirates showed slight changes in six patients, with only an increased number of mast cells in an additional patient. The disease tended to resolve spontaneously. This prospective study emphasizes the benign nature of pediatric urticaria pigmentosa.

引用

页码：102 / 106

页数：5

共 36 条

[31] Cryer PE, Kissane JM, Clinicopathologic conference: systemic mastocytosis, Am J Med, 61, pp. 671-680, (1976)
[32] Lucaya J, Perez-Candela V, Celestina A, Calvo J, Mastocytosis with skeletal and gastrointestinal involvement in infancy. Two case reports and a review of the literature, Radiology, 131, pp. 363-366, (1979)
[33] Parker RI, Hematologic aspects of mastocytosis. I. Bone marrow pathology in adult and pediatric systemic mast cell disease, Journal of Investigative Dermatology, 96, pp. 47S-51S, (1991)
[34] Horny HP, Parwaresch MR, Lennert K, Bone marrow findings in systemic mastocytosis, Hum Pathol, 16, pp. 808-814, (1985)
[35] Ridell B, Olafsson JH, Roupe G, Et al., The bone marrow in urticaria pigmentosa and systemic mastocytosis, Arch Dermatol, 122, pp. 422-427, (1986)
[36] Kettelhut BV, Parker RI, Travis WD, Metcalfe DD, Hematopathology of the bone marrow in pediatric cutaneous mastocytosis. A study of 17 patients, Am J Clin Pathol, 91, pp. 558-562, (1989)

← 1 2 3 4 →