CONTRIBUTION OF IMMUNOHISTOCHEMISTRY IN THE DIAGNOSIS OF NEUROENDOCRINE NEOPLASMS OF THE LARYNX

被引:26
作者
FERLITO, A
FRIEDMANN, I
机构
[1] Department of Otolaryngology, University of Padua
[2] Department of Histopathology, Northwick Park Hospital, Harrow
来源
ORL-JOURNAL FOR OTO-RHINO-LARYNGOLOGY AND ITS RELATED SPECIALTIES | 1991年 / 53卷 / 04期
关键词
NEUROENDOCRINE NEOPLASMS; LARYNX; ENDOCRINE TUMORS; IMMUNOHISTOCHEMISTRY;
D O I
10.1159/000276222
中图分类号
R76 [耳鼻咽喉科学];
学科分类号
100213 ;
摘要
This chapter illustrates the use of mono- and polyclonal antibodies as diagnostic tools for neuroendocrine neoplasms of the larynx on the basis of data from the literature and the authors' personal experience. It is suggested that a panel of antibodies should be adopted, rather than to rely on the specificity and sensitivity of a single marker. It is also emphasized that immunohistochemical methods should serve not as a substitute but as a useful adjuvant in evaluating the morphological criteria of these neoplasms.
引用
收藏
页码:235 / 244
页数:10
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