RELEASE OF (C-14)5-HYDROXYTRYPTAMINE FROM HUMAN PLATELETS BY RED WINE

被引:23
作者
JARMAN, J
GLOVER, V
SANDLER, M
机构
[1] Department of Chemical Pathology, Queen Charlotte's and Chelsea Hospital, London, W6 OXG, Goldhawk Road
关键词
D O I
10.1016/0024-3205(91)90265-D
中图分类号
R-3 [医学研究方法]; R3 [基础医学];
学科分类号
1001 ;
摘要
Red wine, at a final dilution of 1/50, caused release of [C-14]5-hydroxytryptamine (5-HT) from preloaded platelets, an effect which was not observed with any white wines or beers tested. Since 5-HT, is probably released from body stores during migraine attacks and red wine is known to provoke migraine episodes in susceptible individuals, release of 5-HT, possibly from central stores, could represent a plausible mechanism for its mode of action.
引用
收藏
页码:2297 / 2300
页数:4
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