MALAYSIATIN, THE 1ST CYCLIC HEPTAPEPTIDE FROM A MARINE SPONGE

被引:15
作者
FERNANDEZ, R
OMAR, S
FELIZ, M
QUINOA, E
RIGUERA, R
机构
[1] UNIV SANTIAGO DE COMPOSTELA, FAC QUIM, DEPT QUIM ORGAN, E-15706 SANTIAGO, SPAIN
[2] UNIV KEBANGSAAN MALAYSIA, SABAH, MALAYSIA
[3] UNIV BARCELONA, FAC QUIM, DEPT QUIM ORGAN, E-08028 BARCELONA, SPAIN
关键词
D O I
10.1016/S0040-4039(00)61115-2
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
Malaysiatin (1), the first homodetic cycloheptapeptide from a marine source, has been isolated from the cytotoxic and antimicrobial extracts of the marine sponge Pseudaxinyssa sp., collected in Borneo. The unusual structure of malaysiatin, which contains homodipeptide and homotripeptide fragments, was elucidated by extensive spectroscopic analysis that suggests an all-L stereochemistry.
引用
收藏
页码:6017 / 6020
页数:4
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