BIOSYNTHESIS OF PTERIDINES IN SKIN OF TADPOLE RANA CATESBEIANA

被引：18

作者：

SUGIURA, K

GOTO, M

机构：

[1] Department of Chemistry, Gakushuin University, Toshima-ku, Tokyo

来源：

JOURNAL OF BIOCHEMISTRY | 1968年 / 64卷 / 05期

关键词：

D O I：

10.1093/oxfordjournals.jbchem.a128944

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Biosynthesis of biopterin in the skin of the tadpole, Rana catesbeianawas investigated with guanosine-14C(U), neopterin-8a-14C, 7,8-dihydroneopterin- 8a-14C, neopterin-3'-phosphate-8a-14C and 7, 8-dihydro-2-amino- 4-hydroxypteridine-8a-14C. It was found that after incubating any of these compounds with tadpole skins radioactive biopterin could be isolated. Neopterin-3'-phosphate-8a-14C and 7,8-dihydroneopterin were both incorporated into biopterin more effectively than neopterin. Thus, it was postulated that dihydroneopterin-3'-phosphate or its pyrophosphate might be a direct precursor of biopterin. © 1968 by the Journal of Biochemistry.

引用

页码：657 / &

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