BIOSYNTHESIS OF PTERIDINES IN SKIN OF TADPOLE RANA CATESBEIANA

被引：18

作者：

SUGIURA, K

GOTO, M

机构：

[1] Department of Chemistry, Gakushuin University, Toshima-ku, Tokyo

来源：

JOURNAL OF BIOCHEMISTRY | 1968年 / 64卷 / 05期

关键词：

D O I：

10.1093/oxfordjournals.jbchem.a128944

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Biosynthesis of biopterin in the skin of the tadpole, Rana catesbeianawas investigated with guanosine-14C(U), neopterin-8a-14C, 7,8-dihydroneopterin- 8a-14C, neopterin-3'-phosphate-8a-14C and 7, 8-dihydro-2-amino- 4-hydroxypteridine-8a-14C. It was found that after incubating any of these compounds with tadpole skins radioactive biopterin could be isolated. Neopterin-3'-phosphate-8a-14C and 7,8-dihydroneopterin were both incorporated into biopterin more effectively than neopterin. Thus, it was postulated that dihydroneopterin-3'-phosphate or its pyrophosphate might be a direct precursor of biopterin. © 1968 by the Journal of Biochemistry.

引用

页码：657 / &

共 30 条

[11]

HAMA T, 1964, 1962 PTER CHEM P S, P495

[12]

JONES THD, 1967, J BIOL CHEM, V242, P3989

[13]

KAUFMAN S, 1967, J BIOL CHEM, V242, P3934

[14] PTERIDINE COFACTORS [J].

KAUFMAN, S .

ANNUAL REVIEW OF BIOCHEMISTRY, 1967, 36 :171-&

[15]

KIDDER GW, 1968, J BIOL CHEM, V243, P826

[16] HETEROCYCLEN IM STOFFWECHSEL .2. DIE SYNTHESE VON CYANESSIGSAURE-METHYLESTER-[3-C-14] [J].

KORTE, F ;

BARKEMEYER, H .

CHEMISCHE BERICHTE-RECUEIL, 1957, 90 (03) :392-395

[17]

LEVY CC, 1964, J BIOL CHEM, V239, P560

[18] ORIGIN OF SIDE-CHAIN IN PTERIDINES OF BIOPTERIN TYPE [J].

MACLEAN, FI ;

FORREST, HS ;

MYERS, J .

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1965, 18 (04) :623-&

[19] SEPIAPTERIN REDUCTASE [J].

MATSUBARA, M ;

KATOH, S ;

AKINO, M ;

KAUFMAN, S .

BIOCHIMICA ET BIOPHYSICA ACTA, 1966, 122 (02) :202-+

[20] THE STRUCTURE OF THE LIVER L-CASEI FACTOR [J].

MOWAT, JH ;

BOOTHE, JH ;

HUTCHINGS, BL ;

STOKSTAD, ELR ;

WALLER, CW ;

ANGIER, RB ;

SEMB, J ;

COSULICH, DB ;

SUBBAROW, Y .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1948, 70 (01) :14-18

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