SURFACTIN ITURIN-A INTERACTIONS MAY EXPLAIN THE SYNERGISTIC EFFECT OF SURFACTIN ON THE BIOLOGICAL PROPERTIES OF ITURIN-A

被引：140

作者：

MAGETDANA, R ^{[1
]}

THIMON, L ^{[1
]}

PEYPOUX, F ^{[1
]}

PTAK, M ^{[1
]}

机构：

[1] UNIV LYON 1,BIOCHIM MICROBIENNE LAB,F-69622 VILLEURBANNE,FRANCE

来源：

BIOCHIMIE | 1992年 / 74卷 / 12期

关键词：

ITURIN-A; SURFACTIN; ANTIBIOTIC LIPOPEPTIDES; BIOSURFACTANT; SYNERGISM; MONOMOLECULAR FILM; MIXED MONOLAYERS;

D O I：

10.1016/0300-9084(92)90002-V

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Iturin A and surfactin are two lipopeptides extracted from a same strain of Bacillus subtilis. Iturin A possesses antibiotic and antifungal activities and surfactin is a strong surfactant. The presence of surfactin, at a concentration at which, alone, it is inactive, increases to a very large extent the haemolysis percent induced by iturin A. This synergistic effect seems to be in relation with interactions between iturin A and surfactin. Iturin A adsorbs to and penetrates into surfactin monolayers. Iturin A and surfactin are miscible and interact specifically in mixed monolayers.

引用

页码：1047 / 1051

页数：5

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