EFFECT OF FOOD ON ABSORPTION OF LOMEFLOXACIN

被引：22

作者：

HOOPER, WD

DICKINSON, RG

EADIE, MJ

机构：

[1] Department of Medicine, University of Queensland, Royal Brisbane Hospital, Herston

来源：

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY | 1990年 / 34卷 / 09期

关键词：

D O I：

10.1128/AAC.34.9.1797

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

Twelve subjects participated in an open-label, single-dose, balanced three-way crossover study in which the absorptions of lomefloxacin were compared following (i) an overnight fast, (ii) a carbohydrate meal, and (iii) a high-fat meal. The time to peak concentration of lomefloxacin was delayed, but peak concentration in plasma and amount of drug absorbed were unchanged following both meals.

引用

页码：1797 / 1799

页数：3

共 5 条

[1] OFLOXACIN - SERUM AND SKIN BLISTER FLUID PHARMACOKINETICS IN THE FASTING AND NONFASTING STATE [J].