BETA-ENDORPHIN - REPLACEMENT OF GLUTAMIC-ACID IN POSITION-8 BY GLUTAMINE INCREASES ANALGESIC POTENCY AND OPIATE RECEPTOR-BINDING ACTIVITY

被引：11

作者：

LI, CH ^{[1
]}

YAMASHIRO, D ^{[1
]}

HAMMONDS, RG ^{[1
]}

NICOLAS, P ^{[1
]}

TSENG, LF ^{[1
]}

机构：

[1] MED COLL WISCONSIN,DEPT PHARMACOL,MILWAUKEE,WI 53226

来源：

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS | 1981年 / 101卷 / 01期

关键词：

D O I：

10.1016/S0006-291X(81)80018-6

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

引用

页码：118 / 123

页数：6

共 21 条

[1]

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[2]

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[3] USE OF CHLORINATED BENZYLOXYCARBONYL PROTECTING GROUPS TO ELIMINATE N-EPSILON-BRANCHING AT LYSINE DURING SOLID-PHASE PEPTIDE SYNTHESIS [J].

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[4] BETA-ENDORPHIN - CHARACTERISTICS OF BINDING-SITES IN THE RAT-BRAIN [J].

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[5]

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[6]

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[7] BETA-ENDORPHIN-(1-27) - ACETYLATION OF ALPHA-AMINO GROUPS ENHANCES IMMUNOREACTIVITY BUT DIMINISHES ANALGESIC AND RECEPTOR-BINDING ACTIVITIES WITH NO CHANGES IN CIRCULAR-DICHROISM SPECTRA [J].

LI, CH ;

TSENG, LF ;

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HAMMONDS, RG ;

YAMASHIRO, D ;

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BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1980, 97 (03) :932-938

[8] SYNTHESIS AND ANALGESIC ACTIVITY OF HUMAN BETA-ENDORPHIN [J].

LI, CH ;

YAMASHIRO, D ;

TSENG, LF ;

LOH, HH .

JOURNAL OF MEDICINAL CHEMISTRY, 1977, 20 (03) :325-328

[9] ISOLATION AND STRUCTURE OF AN UNTRIAKONTAPEPTIDE WITH OPIATE ACTIVITY FROM CAMEL PITUITARY-GLANDS [J].

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CHUNG, D .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1976, 73 (04) :1145-1148

[10] BETA-ENDORPHIN - DISSOCIATION OF RECEPTOR-BINDING ACTIVITY FROM ANALGESIC POTENCY [J].

LI, CH ;

TSENG, LF ;

FERRARA, P ;

YAMASHIRO, D .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA-BIOLOGICAL SCIENCES, 1980, 77 (04) :2303-2304

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