CHEMOTHERAPY OF BACTERIAL PLASMIDS

被引：11

作者：

HAHN, FE

机构：

[1] Division of Communicable Disease and Immunology, Walter Reed Army Institute of Research, Washington, D.C.

来源：

NATURWISSENSCHAFTEN | 1979年 / 66卷 / 11期

关键词：

D O I：

10.1007/BF00368809

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Pharmacological approaches to plasmid chemotherapy are: 1) discovery of novel antibacterial drugs against which plasmids do not carry resistance genes, 2) molecular modification of existing drugs to render them non-susceptible to plasmid-encoded enzymes, 3) development of drugs which are selective inhibitors of plasmid DNA replication, 4) development of drugs which inhibit phenotypic expression of plasmid genes, and 5) development of drugs which are inhibitors of drug-inactivating enzymes that are plasmid gene products. © 1979 Springer-Verlag.

引用

页码：555 / 562

页数：8