EVIDENCE FOR OLIGOMANNOSYL RESIDUES CONTAINING BOTH BETA-1,2 AND ALPHA-1,2 LINKAGES AS A SEROTYPE-A-SPECIFIC EPITOPE(S) IN MANNANS OF CANDIDA-ALBICANS

被引：77

作者：

KOBAYASHI, H ^{[1
]}

SHIBATA, N ^{[1
]}

SUZUKI, S ^{[1
]}

机构：

[1] TOHOKU COLL PHARMACEUT SCI, DEPT HYG CHEM 2, 4-4-1 KOMATSUSHIMA, AOBA KU, MIYAGI 981, JAPAN

来源：

INFECTION AND IMMUNITY | 1992年 / 60卷 / 05期

关键词：

D O I：

10.1128/IAI.60.5.2106-2109.1992

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

In order to identify the branches containing both beta-1,2 and alpha-1,2 linkages as the serotype A-specific epitope(s) in the mannans of Candida albicans, serotype A strains with oligosaccharides constituting the beta-1,2 linkage, the alpha-1,2 linkage, and both the beta-1,2 and the alpha-1,2 linkages were prepared from the mannans of C. albicans serotype A strains (NIH A-207 and J-1012) and tested for their inhibitory effects in the precipitin and slide agglutination assays. The results indicated that two oligosaccharides containing both beta-1,2 and alpha-1,2 linkages, Manp-beta-1-2Manp-alpha-1-2Manp-alpha-1-2Manp-alpha-1-2Man and Manp-beta-1-2Manp-beta-1-2Manp-alpha-1-2Manp-alpha-1-2Manp-alpha-1-2Man, served as epitopes participating in the serotype A specificity of C. albicans strains.

引用

页码：2106 / 2109

页数：4

共 19 条

[1] RESPONSE AND SPECIFICITY OF ANTIBODIES FOR CANDIDA ALBICANS
FUKAZAWA, Y
SHINODA, T
TSUCHIYA, T
[J]. JOURNAL OF BACTERIOLOGY, 1968, 95 (03) : 754 - +
[2] ANTIGENIC STUDIES OF CANDIDA .1. OBSERVATION OF 2 ANTIGENIC GROUPS IN CANDIDA ALBICANS
HASENCLEVER, H
MITCHELL, WO
[J]. JOURNAL OF BACTERIOLOGY, 1961, 82 (04) : 570 - +
[3] KAGAYA K, 1989, J IMMUNOL, V143, P3353
[4] CANDIDA-ALBICANS SEROTYPE-A STRAINS GROW IN YEAST EXTRACT ADDED SABOURAUD LIQUID-MEDIUM AT PH-2.0, ELABORATING MANNANS WITHOUT BETA-1,2 LINKAGE AND PHOSPHATE GROUP
KOBAYASHI, H
GIUMMELLY, P
TAKAHASHI, S
ISHIDA, M
SATO, J
TAKAKU, M
NISHIDATE, Y
SHIBATA, N
OKAWA, Y
SUZUKI, S
[J]. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1991, 175 (03) : 1003 - 1009
[5] STRUCTURAL DETERMINATION OF D-MANNANS OF PATHOGENIC YEASTS CANDIDA-STELLATOIDEA TYPE-I STRAINS - TIMM-0310 AND ATCC-11006 COMPARED TO IFO-1397
KOBAYASHI, H
KOJIMAHARA, T
TAKAHASHI, K
TAKIKAWA, M
TAKAHASHI, SI
SHIBATA, N
OKAWA, Y
SUZUKI, S
[J]. CARBOHYDRATE RESEARCH, 1991, 214 (01) : 131 - 145
[6] STRUCTURAL STUDY OF PHOSPHOMANNAN OF YEAST-FORM CELLS OF CANDIDA-ALBICANS J-1012 STRAIN WITH SPECIAL REFERENCE TO APPLICATION OF MILD ACETOLYSIS
KOBAYASHI, H
SHIBATA, N
MITOBE, H
OHKUBO, Y
SUZUKI, S
[J]. ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS, 1989, 272 (02) : 364 - 375
[7] STRUCTURAL STUDY OF CELL-WALL PHOSPHOMANNAN OF CANDIDA-ALBICANS NIH-B-792 (SEROTYPE-B) STRAIN, WITH SPECIAL REFERENCE TO H-1 AND C-13 NMR ANALYSES OF ACID-LABILE OLIGOMANNOSYL RESIDUES
KOBAYASHI, H
SHIBATA, N
NAKADA, M
CHAKI, S
MIZUGAMI, K
OHKUBO, Y
SUZUKI, S
[J]. ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS, 1990, 278 (01) : 195 - 204
[8] KOBAYASHI H, IN PRESS PHYTOCHEMIS
[9] KOBAYASHI H, IN PRESS ARCH BIOCH
[10] KOBAYASHI H, IN PRESS CARBOHYDR R

← 1 2 →