NONISOTOPIC RECEPTOR-BINDING ASSAY FOR BENZODIAZEPINE RECEPTORS UTILIZING A FLUOROPHORE LABELED LIGAND

被引：17

作者：

TAKEUCHI, T ^{[1
]}

RECHNITZ, GA ^{[1
]}

机构：

[1] UNIV HAWAII,DEPT CHEM,HAWAII BIOSENSOR LAB,HONOLULU,HI 96822

来源：

ANALYTICAL BIOCHEMISTRY | 1991年 / 194卷 / 02期

关键词：

D O I：

10.1016/0003-2697(91)90226-J

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

A nonisotopic receptor-binding assay method provides a new approach for the study of receptor-ligand interactions and a possible receptor assay for benzodiazepine drugs. The proposed method is based upon the use of fluorescence-labeled drugs and a chromatographic system which accepts samples without deproteinization. The effectiveness of the technique is illustrated in a study of benzodiazepine receptor-drug-binding interactions. © 1991.

引用

页码：250 / 255

页数：6

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