CALCIUM-BINDING INDUCES CONFORMATIONAL-CHANGES IN MUSCLE REGULATORY PROTEINS

被引：108

作者：

DASILVA, ACR

REINACH, FC

机构：

[1] A.C.R. da Silva and F.C. Reinach are, the Departamento de Bioquimica, Instituto de Quimica, CEP 01498 Sao Paulo, SP

来源：

TRENDS IN BIOCHEMICAL SCIENCES | 1991年 / 16卷 / 02期

基金：

巴西圣保罗研究基金会;

关键词：

D O I：

10.1016/0968-0004(91)90024-P

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Calcium binding to proteins containing the 'EF-hand' structural motif regulates a variety of biochemical processes including muscle contraction. Techniques such as protein crystallography, site-directed mutagenesis and domain transplantation experiments are being used to unravel the conformational changes induced by calcium binding.

引用

页码：53 / 57

页数：5

共 29 条

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