INVITRO TRANSFORMATION BY THE SV40 EARLY REGION OF CELLS FROM A HUMAN BENIGN SALIVARY-GLAND TUMOR WITH A 12Q13-]Q15 REARRANGEMENT

被引：33

作者：

KAZMIERCZAK, B

BARTNITZKE, S

HARTL, M

BULLERDIEK, J

机构：

[1] UNIV BREMEN,CTR HUMAN GENET,LEOBENER STR NW2,W-2800 BREMEN 33,GERMANY

[2] UNIV MUNICH,INST BIOCHEM,W-8000 MUNICH 2,GERMANY

来源：

CYTOGENETICS AND CELL GENETICS | 1990年 / 53卷 / 01期

关键词：

D O I：

10.1159/000132891

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

Cells from a salivary gland pleomorphic adenoma with a reciprocal translocation. t(8:12)(q22;ql4). were transformed by transfection with a plasmid containing the SV40 “early region.” Compared with nontransformed adenoma cells, the cells expressed large-T antigen, had a higher proliferative capacity. showed a drastically increased or even unlimited growth potential in vitro, and formed colonies in soft agar. The amount of cellular material produced in this way should make possible many experiments at the molecular level that could not be performed before. © 1990 S. Karger AG, Basel.

引用

页码：37 / 39

页数：3

共 19 条

[1] REARRANGEMENTS OF CHROMOSOME REGION 12Q13-]Q15 IN PLEOMORPHIC ADENOMAS OF THE HUMAN SALIVARY-GLAND (PSA)
BULLERDIEK, J
BARTNITZKE, S
WEINBERG, M
CHILLA, R
HAUBRICH, J
SCHLOOT, W
[J]. CYTOGENETICS AND CELL GENETICS, 1987, 45 (3-4): : 187 - 190
[2] STRUCTURAL REARRANGEMENTS OF CHROMOSOME NR-8 INVOLVING 8Q12 - A PRIMARY EVENT IN PLEOMORPHIC ADEMONA OF THE PAROTID-GLAND
BULLERDIEK, J
RAABE, G
BARTNITZKE, S
BOSCHEN, C
SCHLOOT, W
[J]. GENETICA, 1987, 72 (02) : 85 - 92
[3] ABERRATIONS OF CHROMOSOME-8 IN MIXED SALIVARY-GLAND TUMORS - CYTOGENETIC FINDINGS ON 7 CASES
BULLERDIEK, J
BOSCHEN, C
BARTNITZKE, S
[J]. CANCER GENETICS AND CYTOGENETICS, 1987, 24 (02) : 205 - 212
[4] SV 40-INDUCED TRANSFORMATION OF HUMAN DIPLOID CELLS - CRISIS AND RECOVERY
GIRARDI, AJ
JENSEN, FC
KOPROWSKI, H
[J]. JOURNAL OF CELLULAR AND COMPARATIVE PHYSIOLOGY, 1965, 65 (01): : 69 - +
[5] COMPLEX OF SIMIAN VIRUS-40 LARGE-T ANTIGEN AND HOST 53,000-MOLECULAR-WEIGHT PROTEIN IN MONKEY CELLS
HARLOW, E
PIM, DC
CRAWFORD, LV
[J]. JOURNAL OF VIROLOGY, 1981, 37 (02) : 564 - 573
[6] RECIPROCAL TRANSLOCATION T(3-12)(Q27-Q13) IN LIPOMA
HEIM, S
MANDAHL, N
KRISTOFFERSSON, U
MITELMAN, F
ROOSER, B
RYDHOLM, A
WILLEN, H
[J]. CANCER GENETICS AND CYTOGENETICS, 1986, 23 (04) : 301 - 304
[7] A SPECIFIC TRANSLOCATION, T(12,14)(Q14-15,Q23-24), CHARACTERIZES A SUBGROUP OF UTERINE LEIOMYOMAS
HEIM, S
NILBERT, M
VANNI, R
FLODERUS, UM
MANDAHL, N
LIEDGREN, S
LECCA, U
MITELMAN, F
[J]. CANCER GENETICS AND CYTOGENETICS, 1988, 32 (01) : 13 - 17
[8] SV40-TRANSFORMED HUMAN-FIBROBLASTS EXHIBIT A CHARACTERISTIC CHROMOSOMAL PATTERN
HOFFSCHIR, F
RICOUL, M
DUTRILLAUX, B
[J]. CYTOGENETICS AND CELL GENETICS, 1988, 49 (04): : 264 - 268
[9] 3 MAJOR CYTOGENETIC SUBGROUPS CAN BE IDENTIFIED AMONG CHROMOSOMALLY ABNORMAL SOLITARY LIPOMAS
MANDAHL, N
HEIM, S
ARHEDEN, K
RYDHOLM, A
WILLEN, H
MITELMAN, F
[J]. HUMAN GENETICS, 1988, 79 (03) : 203 - 208
[10] SIGNIFICANCE OF THE CHOICE OF TISSUE-CULTURE TECHNIQUE ON THE CHROMOSOMAL PATTERNS IN HUMAN MIXED SALIVARY-GLAND TUMORS
MARK, J
SANDROS, J
WEDELL, B
STENMAN, G
EKEDAHL, C
[J]. CANCER GENETICS AND CYTOGENETICS, 1988, 33 (02) : 229 - 244

← 1 2 →