REPRODUCTION AND THE RENIN-ANGIOTENSIN SYSTEM

被引：52

作者：

GANONG, WF

机构：

[1] Department of Physiology, University of California, San Francisco

来源：

NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS | 1995年 / 19卷 / 02期

关键词：

RENIN; ANGIOTENSIN; ANGIOTENSINOGEN; REPRODUCTION; HYPOTHALAMUS; OVARIES; TESTES; UTERUS;

D O I：

10.1016/0149-7634(94)00056-7

中图分类号：

B84 [心理学]; C [社会科学总论]; Q98 [人类学];

学科分类号：

03 ; 0303 ; 030303 ; 04 ; 0402 ;

摘要：

A unique aspect of the circulating renin-angiotensin system and the many independent tissue renin-angiotensin systems is their interactions at multiple levels with reproduction. These interactions, which have received relatively little attention, include effects of estrogens and possibly androgens on hepatic and renal angiotensinogen mRNA; effects of androgens on the Ren-2 gene and salivary renin in mice; the prorenin surge that occurs with but outlasts the LH surge during the menstrual cycle; the inhibitory effects of estrogens on thirst and water intake; the tissue renin-angiotensin systems in the brain, the anterior pituitary, and the ovaries and testes, that is, in all the components of the hypothalamo-pituitary-gonadal axis; the presence of some components of the renin-angiotensin system in the uterus and the fetoplacental unit; and the possible relation of renin and angiotensin to ovulation and fetal well-being. These interactions are described and their significance considered in this short review.

引用

页码：241 / 250

页数：10

共 103 条

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