DEOXYRIBONUCLEIC-ACID STRUCTURES VISUALIZED BY SCANNING TUNNELING MICROSCOPY

被引：15

作者：

BENDIXEN, C ^{[1
]}

BESENBACHER, F ^{[1
]}

LAEGSGAARD, E ^{[1
]}

STENSGAARD, I ^{[1
]}

THOMSEN, B ^{[1
]}

WESTERGAARD, O ^{[1
]}

机构：

[1] AARHUS UNIV,INST PHYS,DK-8000 AARHUS C,DENMARK

来源：

JOURNAL OF VACUUM SCIENCE & TECHNOLOGY A-VACUUM SURFACES AND FILMS | 1990年 / 8卷 / 01期

关键词：

D O I：

10.1116/1.576987

中图分类号：

TB3 [工程材料学];

学科分类号：

0805 ; 080502 ;

摘要：

The capability of the scanning tunneling microscope (STM) to produce atomic-resolution images makes it a powerful tool in both basic and applied science. The main application of STM has been for the analysis of structural features and electronic properties of a wide spectrum of metals and semiconductors, while only a few biological items have been investigated. With a STM operating in air at ambient pressure, we present images showing the molecular structure of naked DNA. High-resolution topographic images of linear DNA fragments reveal structures with a periodicity of ~ 38 ± 6 A and a width of 28 + 4 A, consistent with the molecular dimensions of the helical repeat of double-stranded DNA. In addition, the supreme resolving power of the STM permits visualization of the major and minor grooves. © 1990, American Vacuum Society. All rights reserved.

引用

页码：703 / 705

页数：3

共 27 条

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