CIPROFLOXACIN DOES NOT INHIBIT MITOCHONDRIAL FUNCTIONS BUT OTHER ANTIBIOTICS DO

被引：50

作者：

RIESBECK, K ^{[1
]}

BREDBERG, A ^{[1
]}

FORSGREN, A ^{[1
]}

机构：

[1] UNIV LUND, MALMO GEN HOSP, DEPT MED MICROBIOL, S-21401 MALMO, SWEDEN

来源：

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY | 1990年 / 34卷 / 01期

关键词：

D O I：

10.1128/AAC.34.1.167

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

At clinical concentrations, ciprofloxacin did not inhibit mitochondrial DNA replication, oxidative phosphorylation, protein synthesis, or mitochondrial mass (transmembrane potential). No difference in supercoiled forms of DNA was observed. The tetracyclines and chloramphenicol inhibited protein synthesis at clinically achievable concentrations, while rifampin, fusidic acid, and clindamycin did not.

引用

页码：167 / 169

页数：3

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