LINTENOLIDES, NEW PENTACYCLIC BIOACTIVE SESTERTERPENES FROM THE CARIBBEAN SPONGE CACOSPONGIA CF LINTEIFORMIS

被引：26

作者：

CONTE, MR ^{[1
]}

FATTORUSSO, E ^{[1
]}

LANZOTTI, V ^{[1
]}

MAGNO, S ^{[1
]}

MAYOL, L ^{[1
]}

机构：

[1] UNIV MOLISE, DIPARTIMENTO SCI & TECNOL AGROALIMENTARI AMBIENT, I-86100 CAMPOBASSO, ITALY

来源：

TETRAHEDRON | 1994年 / 50卷 / 03期

关键词：

D O I：

10.1016/S0040-4020(01)80799-7

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

New pentacyclic sesterterpenes, lintenolide A (2 a, b) and lintenolide B (3 a, b), have been characterized from the caribbean sponge Cacospongia cf. linteiformis. The structure elucidation of these compounds was accomplished by using 2D NMR experiments, including H-1-H-1 (COSY), H-1-C-13 (HETCORR and COLOC) and rotating frame NOE (ROESY). Compounds showed high ichthyotoxicity and antifeedant activity, which suggest their potential role as natural feeding deterrents.

引用

页码：849 / 856

页数：8

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