Contrast-enhanced synthetic MRI for the detection of brain metastases

被引：51

作者：

Hagiwara, Akifumi ^{[1
,2
]}

Hori, Masaaki ^{[1
]}

Suzuki, Michimasa ^{[1
]}

Andica, Christina ^{[1
]}

Nakazawa, Misaki ^{[1
,3
]}

Tsuruta, Kouhei ^{[1
,3
]}

Takano, Nao ^{[1
]}

Sato, Shuji ^{[1
]}

Hamasaki, Nozomi ^{[1
]}

Yoshida, Mariko ^{[1
]}

Kumamaru, Kanako Kunishima ^{[1
]}

Ohtomo, Kuni ^{[2
]}

Aoki, Shigeki ^{[1
]}

机构：

[1] Juntendo Univ, Sch Med, Dept Radiol, Tokyo 113, Japan

[2] Univ Tokyo, Grad Sch Med, Dept Radiol, Tokyo, Japan

[3] Tokyo Metropolitan Univ, Grad Sch Human Hlth Sci, Dept Radiol Sci, Tokyo 158, Japan

来源：

ACTA RADIOLOGICA OPEN | 2016年 / 5卷 / 02期

关键词：

Magnetic resonance imaging (MRI); synthetic MRI; contrast-enhanced MRI; T1-weighted inversion recovery; metastases; brain;

D O I：

10.1177/2058460115626757

中图分类号：

R8 [特种医学]; R445 [影像诊断学];

学科分类号：

1002 [临床医学]; 100207 [影像医学与核医学]; 1009 [特种医学];

摘要：

Background Synthetic magnetic resonance imaging (MRI), a technique that enables creation of various contrast-weighted images from a single MRI quantification scan, is a useful clinical tool. However, there are currently no reports examining the use of contrast-enhanced synthetic MRI for detecting brain metastases. Purpose To assess whether contrast-enhanced synthetic MRI is suitable for detecting brain metastases. Material and Methods Ten patients with a combined total of 167 brain metastases who underwent quantitative MRI and conventional T1-weighted inversion recovery fast spin-echo (conventional T1IR) MRI before and after administration of a contrast agent were included in the study. Synthetic T1IR and T1-weighted (synthetic T1W) images were produced after parameter quantification. Lesion-to-white matter contrast and contrast-to-noise ratio were calculated for each image. The number of visible lesions in each image was determined by two neuroradiologists. Results The mean lesion-to-white matter contrast and mean contrast-to-noise ratio of the synthetic T1IR images were significantly higher than those of the synthetic T1W (P<0.001 and P<0.001, respectively) and conventional T1IR (P=0.04 and P=0.002, respectively) images. Totals of 130 and 124 metastases were detected in the synthetic T1IR images by the first and second radiologists, respectively. The corresponding numbers were 91 and 85 in the synthetic T1W images and 119 and 119 in the conventional T1IR images. Statistical significance was not found among detected numbers of lesions. Conclusion Synthetic T1IR imaging created better contrast compared with synthetic T1W or conventional T1IR imaging. The ability to detect brain metastases was comparable among these imaging.

引用

页数：6

共 17 条

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