THE CATALYTIC ASYMMETRIC ALDOL REACTION OF ALDEHYDES WITH UNSUBSTITUTED AND MONOSUBSTITUTED SILYL KETENE ACETALS - FORMATION OF ANTI-BETA-HYDROXY-ALPHA-METHYL ESTERS

被引：89

作者：

PARMEE, ER ^{[1
]}

HONG, YP ^{[1
]}

TEMPKIN, O ^{[1
]}

MASAMUNE, S ^{[1
]}

机构：

[1] MIT,DEPT CHEM,CAMBRIDGE,MA 02139

来源：

TETRAHEDRON LETTERS | 1992年 / 33卷 / 13期

基金：

美国国家卫生研究院;

关键词：

D O I：

10.1016/S0040-4039(00)91717-9

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The title reaction with unsubstituted and monosubstituted silyl ketene acetals proceeds with high enantioselectivity, and in the latter case good diastereoselectivity favoring the anti-beta-hydroxy-alpha-methyl esters in all reported cases.

引用

页码：1729 / 1732

页数：4

共 16 条

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