REGULATION OF ISOTYPE SWITCHING

被引：54

作者：

VERCELLI, D ^{[1
]}

GEHA, RS ^{[1
]}

机构：

[1] HARVARD UNIV,SCH MED,BOSTON,MA 02115

来源：

CURRENT OPINION IN IMMUNOLOGY | 1992年 / 4卷 / 06期

关键词：

D O I：

10.1016/0952-7915(92)90064-L

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

In the past year, our understanding of the mechanisms that regulate isotype switching has significantly progressed. Activation of germ line transcription by isotype-specific cytokines is emerging as a crucial mechanism for increasing the accessibility of a particular switch region, and targeting switch recombination.

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收藏

页码：794 / 797

页数：4

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