LIPOSOMES, MURAMYL DIPEPTIDE DERIVATIVES, AND NONTOXIC LIPID A DERIVATIVES AS ADJUVANTS FOR HUMAN MALARIA VACCINES

被引：19

作者：

HUI, GSN ^{[1
]}

机构：

[1] UNIV HAWAII, DEPT TROP MED, HONOLULU, HI 96822 USA

来源：

AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE | 1994年 / 50卷 / 04期

关键词：

D O I：

10.4269/ajtmh.1994.50.41

中图分类号：

R1 [预防医学、卫生学];

学科分类号：

1004 ; 120402 ;

摘要：

Studies indicate that adjuvant formulations based on liposomes, nontoxic lipid A, and muramyl peptide derivatives are safe and effective for vaccine use. Future research on the immunobiology of these adjuvants as well as the mechanisms by which adjuvants can alter the quality of immune responses may play an important role in determining their efficacy in malaria vaccines.

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页码：41 / 51

页数：11

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