LIQUID-CHROMATOGRAPHIC RESOLUTION OF ENANTIOMERS ON CHIRAL AMIDE BONDED SILICA GEL NORMAL PHASE - SEPARATION OF RACEMIC ALPHA-AMINO-ACID DERIVATIVES BY N-ACETYL-L-VALYL-AMINOPROPYL-SILANIZED SILICA (AVA) PHASE

A new optically active stationary phase obtained by grafting N-acetyl-L-valine with 3-aminopropylsilanized silica was developed. The high-efficiency chiral column was prepared by slurry packing procedure. Direct resolution of the racemates of a-amino acid derivatives was accomplished by using normal phase liquid chromatography. Copyright © 1979, Taylor & Francis Group, LLC. All rights reserved.