A POTENT CYCLIC HEXAPEPTIDE ANALOG OF SOMATOSTATIN

被引：396

作者：

VEBER, DF ^{[1
]}

FREIDINGER, RM ^{[1
]}

PERLOW, DS ^{[1
]}

PALEVEDA, WJ ^{[1
]}

HOLLY, FW ^{[1
]}

STRACHAN, RG ^{[1
]}

NUTT, RF ^{[1
]}

ARISON, BH ^{[1
]}

HOMNICK, C ^{[1
]}

RANDALL, WC ^{[1
]}

GLITZER, MS ^{[1
]}

SAPERSTEIN, R ^{[1
]}

HIRSCHMANN, R ^{[1
]}

机构：

[1] MERCK SHARP & DOHME,RES LABS,RAHWAY,NJ 07065

来源：

NATURE | 1981年 / 292卷 / 5818期

关键词：

D O I：

10.1038/292055a0

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

引用

页码：55 / 58

页数：4

共 13 条

[1] INFERENCES ABOUT THE CONFORMATION OF SOMATOSTATIN AT A BIOLOGIC RECEPTOR BASED ON NMR-STUDIES
ARISON, BH
HIRSCHMANN, R
VEBER, DF
[J]. BIOORGANIC CHEMISTRY, 1978, 7 (04) : 447 - 451
[2] CRYSTAL-STRUCTURE AND MOLECULAR-CONFORMATION OF HYDRATED CYCLIC HEXAPEPTIDE CYCLO(L-ALA-L-PRO-D-PHE)2
BROWN, JN
TELLER, RG
[J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1976, 98 (24) : 7565 - 7569
[3] CONFORMATION OF LL AND LD HAIRPIN BENDS WITH INTERNAL HYDROGEN-BONDS IN PROTEINS AND PEPTIDES
CHANDRASEKARAN, R
LAKSHMINARAYANAN, AV
PANDYA, UV
RAMACHANDRAN, GN
[J]. BIOCHIMICA ET BIOPHYSICA ACTA, 1973, 303 (01) : 14 - 27
[4] FINNEY DJ, 1964, STATISTICAL METHOD B, P99
[5] SOMATOSTATIN MODULATION OF GLUCAGON-SECRETION AND ITS IMPORTANCE IN HUMAN GLUCOSE HOMEOSTASIS
GERICH, JE
[J]. METABOLISM-CLINICAL AND EXPERIMENTAL, 1978, 27 (09): : 1283 - 1290
[6] 3-DIMENSIONAL MOLECULAR MODELING AND DRUG DESIGN
GUND, P
ANDOSE, JD
RHODES, JB
SMITH, GM
[J]. SCIENCE, 1980, 208 (4451) : 1425 - 1431
[7] CONFORMATION AND CRYSTAL-STRUCTURES OF 2 CYCLOISOMERIC HEXAPEPTIDES - CYCLO-(L-ALANYL-L-ALANYLGLYCYLGLYCYL-L-ALANYLGLYCYL) MONOHYDRATE (I) AND CYCLO-(L-ALANYL-L-ALANYLGLYCYL-L-ALANYLGLYCYLGLYCYL) DIHYDRATE (II)
HOSSAIN, MB
VANDERHELM, D
[J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1978, 100 (16) : 5191 - 5198
[8] SYNTHESIS OF A PROPOSED THYMIC FACTOR
STRACHAN, RG
PALEVEDA, WJ
BERGSTRAND, SJ
NUTT, RF
HOLLY, FW
VEBER, DF
[J]. JOURNAL OF MEDICINAL CHEMISTRY, 1979, 22 (05) : 586 - 588
[9] VALE W, 1980, METH ENZYM, V37, P5
[10] VEBER D, 1979, PEPTIDES STRUCTURE B, P409

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