ENDOMYSIUM AND GLIADIN IGA ANTIBODIES IN CHILDREN WITH CELIAC-DISEASE

被引：26

作者：

LINDQUIST, BL

ROGOZINSKI, T

MOI, H

DANIELSSON, D

OLCEN, P

机构：

[1] OREBRO MED CTR HOSP,DEPT DERMATOL,S-70185 OREBRO,SWEDEN

[2] OREBRO MED CTR HOSP,DEPT CLIN MICROBIOL & IMMUNOL,S-70185 OREBRO,SWEDEN

[3] MED ACAD WARSAW,DEPT DERMATOL,PL-02032 WARSAW,POLAND

来源：

SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY | 1994年 / 29卷 / 05期

关键词：

CELIAC DISEASE; ENDOMYSIUM ANTIBODIES; GLIADIN ANTIBODIES;

D O I：

10.3109/00365529409096837

中图分类号：

R57 [消化系及腹部疾病];

学科分类号：

摘要：

The diagnostic sensitivity and specificity of IgA endomysium antibodies (EmA) and IgA gliadin antibodies (AGA) for coeliac disease (CD) were studied in Swedish children. Indirect immunofluorescence was used for demonstration of EmA and the diffusion-in-gel enzyme-linked immunosorbent assay method for AGA. Serum samples were collected and analysed from 77 consecutive children undergoing small-intestinal biopsy on recognized clinical indications. The diagnostic sensitivity for CD was 98.1% for EmA and 86.5% for AGA. The specificity of the two tests was 92.7% for EmA and 92.7% for AGA in paediatric patients. In addition, 115 sera from control children showed 2.6% positive for EmA and 0.9% positive for AGA.

引用

页码：452 / 456

页数：5

共 29 条

[11] PRESENCE OF IGA AND IGG ANTIGLIADIN ANTIBODIES IN HEALTHY-ADULTS AS MEASURED BY MICRO-ELISA - EFFECT OF VARIOUS CUTOFF LEVELS ON SPECIFICITY AND SENSITIVITY WHEN DIAGNOSING CELIAC-DISEASE [J].