HYPOTHERMIA IN ACUTE BLUNT HEAD-INJURY

被引：11

作者：

CANCIO, LC

WORTHAM, WG

ZIMBA, F

机构：

[1] General Surgery Service, Brooke Army Medical Center, Fort Sam Houston

[2] Department of Medicine, Brooke Army Medical Center, Fort Sam Houston

[3] Neurosurgery Service, Brooke Army Medical Center, Fort Sam Houston

来源：

RESUSCITATION | 1994年 / 28卷 / 01期

关键词：

HEAD INJURIES; CLOSED; BRAIN INJURIES; HYPOTHERMIA; INDUCED;

D O I：

10.1016/0300-9572(94)90049-3

中图分类号：

R4 [临床医学];

学科分类号：

1002 ; 100602 ;

摘要：

Mild to moderate hypothermia has been employed since the 1940s in the treatment of acute blunt head trauma. The utility of hypothermia in ischemic injury has been confirmed, by both animal studies and clinical experience, in cardiovascular and neurological surgery. In blunt injury, though, only one prospective, randomized study has shown a statistically significant improvement in long term outcome. Clinical experience, animal data, proposed mechanisms, technical considerations, and potential risks are reviewed. Hypothermia remains controversial in the setting of blunt head injury but may prove to be a useful treatment modality.

引用

页码：9 / 19

页数：11

共 153 条

[1] Fay, Observations on generalized refrigeration in cases of severe cerebral trauma, Assoc Res New Men Dis Proc, 24, pp. 611-619, (1945)
[2] Smith, Fay, Temperature factors in cancer and embryonal cell growth, Journal of the American Medical Association, 113, pp. 653-660, (1939)
[3] Fay, Observations on prolonged human refrigeration, NY State J Med, 40, (1940)
[4] Fay, Early experiences with local and generalized refrigeration of the human brain, J Neurosurg, 16, pp. 239-260, (1959)
[5] Fay, Smith, Observations on reflex responses during prolonged periods of human refrigeration, Archives of Neurology And Psychiatry, 45, pp. 215-222, (1941)
[6] Clifton, Allen, Plenger, Berry, Koch, A phase II study of systemic hypothermia in severe brain injury [abstract], J Neurosurg, 78, (1993)
[7] Teasdale, Jennett, Assessment of coma and impaired consciousness: a practical scale, Lancet, 2, pp. 81-84, (1974)
[8] Marion, Obrist, Carlier, Penrod, Darby, The use of moderate hypothermia for patients with severe head injuries: a preliminary report, J Neurosurg, 79, pp. 354-362, (1993)
[9] Shiozaki, Sugimoto, Taneda, Yoshida, Iwai, Yoshioka, Et al., Effect of mild hypothermia on uncontrollable intracranial hypertension after severe head injury, J Neurosurg, 79, pp. 363-368, (1993)
[10] McQuiston, Anesthetic problems in cardiac surgery in children, Anesthesiology, 10, pp. 590-600, (1949)

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