HYPOTHERMIA IN ACUTE BLUNT HEAD-INJURY

被引：11

作者：

CANCIO, LC

WORTHAM, WG

ZIMBA, F

机构：

[1] General Surgery Service, Brooke Army Medical Center, Fort Sam Houston

[2] Department of Medicine, Brooke Army Medical Center, Fort Sam Houston

[3] Neurosurgery Service, Brooke Army Medical Center, Fort Sam Houston

来源：

RESUSCITATION | 1994年 / 28卷 / 01期

关键词：

HEAD INJURIES; CLOSED; BRAIN INJURIES; HYPOTHERMIA; INDUCED;

D O I：

10.1016/0300-9572(94)90049-3

中图分类号：

R4 [临床医学];

学科分类号：

1002 ; 100602 ;

摘要：

Mild to moderate hypothermia has been employed since the 1940s in the treatment of acute blunt head trauma. The utility of hypothermia in ischemic injury has been confirmed, by both animal studies and clinical experience, in cardiovascular and neurological surgery. In blunt injury, though, only one prospective, randomized study has shown a statistically significant improvement in long term outcome. Clinical experience, animal data, proposed mechanisms, technical considerations, and potential risks are reviewed. Hypothermia remains controversial in the setting of blunt head injury but may prove to be a useful treatment modality.

引用

页码：9 / 19

页数：11

共 153 条

[51] Natale, D'Alecy, Protection from cerebral ischemia by brain cooling without reduced lactate accumulation in dogs, Stroke, 20, pp. 770-777, (1989)
[52] Minamisawa, Norstrom, Smith, Siesjo, The influence of mild body and brain hypothermia on ischemic brain damage, J Cereb Blood Flow Metab, 10, pp. 365-374, (1990)
[53] Horn, Schlote, Henrich, Global cerebral ischemia and subsequent selective hypothermia. A neuropathological and morphometrical study on ischemic neuronal damage in cat, Acta Neuropathol, 81, pp. 443-449, (1991)
[54] Baker, Onesti, Solomon, Reduction by delayed hypothermia of cerebral infarction following middle cerebral artery occlusion in the rat
[55] a time-course study, J Neurosurg, 77, pp. 438-444, (1992)
[56] Kader, Brisman, Maraire, Huh, Solomon, The effect of mild hypothermia on permanent focal ischemia in the rat, Neurosurgery, 31, pp. 1056-1061, (1992)
[57] Lo, Steinberg, Effects of hypothermia on evoked potentials, magnetic resonance imaging, and blood flow in focal ischemia in rabbits, Stroke, 23, pp. 889-893, (1992)
[58] Ohta, Sakaguchi, Dong, Nagasawa, Yasuda, Selective cooling of brain using profound hemodilution in dogs, Neurosurgery, 31, pp. 1049-1054, (1992)
[59] Goto, Kassell, Hiramatsu, Soleau, Lee, Effects of intraischemic hypothermia on cerebral damage in a model of reversible focal ischemia, Neurosurgery, 32, pp. 980-985, (1993)
[60] Karibe, Chen, Zarow, Graham, Weinstein, Delayed induction of mild hypothermia to reduce infarct volume after temporary middle artery occlusion in rats, J Neurosurg, 80, pp. 112-119, (1994)

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