PRELIMINARY-REPORT - EFFECT OF GLYCEROL ON TRIGLYCERIDE-METABOLISM IN THE RAT

被引：8

作者：

ABE, R ^{[1
]}

MACDONALD, I ^{[1
]}

MARUHAMA, Y ^{[1
]}

GOTO, Y ^{[1
]}

机构：

[1] GUYS HOSP,SCH MED,DEPT PHYSIOL,LONDON SE1 9RT,ENGLAND

来源：

METABOLISM-CLINICAL AND EXPERIMENTAL | 1979年 / 28卷 / 02期

关键词：

D O I：

10.1016/0026-0495(79)90073-8

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Lipid metabolic studies were carried out on the male Wistar rats fed on glycerol-rich diet in order to elucidate the mechanism of glycerol-induced hypertriglyceridemia. No difference was found between the glycerol fed rats and the control rats in the rate of triglyceride secretion from the liver measured by the Triton WR-1339 method as well as in the rate of incorporation of labeled glycerol into liver triglyceride. The facts that the half-life of the intravenously injected intralipid® in the blood was significantly delayed in the glycerol fed rats and that the lipoprotein lipase activity released from epididymal adipose tissue of the glycerol fed rats was markedly decreased to 19% of that of the control rats seem to account for the serum triglyceride elevation induced by the glycerol feeding. © 1979.

引用

页码：97 / 99

页数：3

共 11 条

[1] GLUCOCORTICOIDS AND TRIGLYCERIDE TRANSPORT - EFFECTS ON TRIGLYCERIDE SECRETION RATES, LIPOPROTEIN-LIPASE, AND PLASMA LIPOPROTEINS IN RAT [J].