BILATERAL IRIS TUMORS IN AN IMMUNOSUPPRESSED CHILD

被引：22

作者：

BRODSKY, MC

CASTEEL, H

BARBER, LD

KLETZL, M

ROLOSON, GJ

机构：

[1] UNIV ARKANSAS MED SCI HOSP,DEPT OPHTHALMOL,LITTLE ROCK,AR 72205

[2] UNIV ARKANSAS MED SCI HOSP,DEPT PEDIAT,LITTLE ROCK,AR 72205

[3] UNIV ARKANSAS MED SCI HOSP,DIV GASTROENTEROL,LITTLE ROCK,AR 72205

[4] UNIV ARKANSAS MED SCI HOSP,DIV HEMATOL ONCOL,LITTLE ROCK,AR 72205

[5] UNIV ARKANSAS MED SCI HOSP,DEPT PATHOL,LITTLE ROCK,AR 72205

来源：

SURVEY OF OPHTHALMOLOGY | 1991年 / 36卷 / 03期

关键词：

CYCLOSPORINE-A; EPSTEIN-BARR VIRUS; IMMUNE DISORDERS; IRIS TUMORS; POSTTRANSPLANT LYMPHOPROLIFERATIVE DISORDERS;

D O I：

10.1016/0039-6257(91)90004-Y

中图分类号：

R77 [眼科学];

学科分类号：

100212 ;

摘要：

A seven-year-old iatrogenically immunosuppressed girl developed simultaneous bilateral iris tumors associated with granulomatous iridocyclitis, splenomegaly, and an immunoblastic pleocytosis. Serologic studies suggested a current active Epstein-Barr virus infection. Tumor biopsy showed a polyclonal plasmacytoid lymphoproliferative process, establishing the diagnosis of posttransplant lymphoproliferative disorder. Low-dose local irradiation produced rapid and complete iris tumor regression with restoration of vision in both eyes. To our knowledge, this is the first report of ocular involvement in posttransplant lymphoproliferative disorder.

引用

页码：217 / 222

页数：6