HIGH-YIELD SYNTHESIS OF LIPID SYSTEMS WITH GIANT RINGS

被引：19

作者：

MENGER, FM

BROCCHINI, S

CHEN, XY

机构：

[1] Department of Chemistry, Emory University, Atlanta, Georgia

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION IN ENGLISH | 1992年 / 31卷 / 11期

关键词：

D O I：

10.1002/anie.199214921

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A high-temperature Glaser coupling reaction is the key to the efficient synthesis of lipids with "giant rings" as exemplified by reaction (a) (77% yield) Macrocyclic compounds are usually considered to have rings with twelve to twenty members: the term "giant rings" refers to compounds with even larger rings.

引用

收藏

页码：1492 / 1493

页数：2

相关论文

共 11 条

[1] INTRAMOLECULAR ACYL RADICAL ALKENE ADDITION-REACTIONS - MACROCYCLIZATION REACTIONS [J].

BOGER, DL ;

MATHVINK, RJ .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1990, 112 (10) :4008-4011

[2]

BOGER DL, 1992, MACROCYCLES

[3] ROTATIONAL AND TRANSLATIONAL DIFFUSION IN MEMBRANES [J].

EDIDIN, M .

ANNUAL REVIEW OF BIOPHYSICS AND BIOENGINEERING, 1974, 3 :179-201

[4] A NEW REAGENT FOR THE REMOVAL OF THE 4-METHOXYBENZYL ETHER - APPLICATION TO THE SYNTHESIS OF UNUSUAL MACROCYCLIC AND BOLAFORM PHOSPHATIDYLCHOLINES [J].

HEBERT, N ;

BECK, A ;

LENNOX, RB ;

JUST, G .

JOURNAL OF ORGANIC CHEMISTRY, 1992, 57 (06) :1777-1783

[5]

Hesse M., 1991, RING ENLARGEMENT ORG

[6] NOVEL MACROLACTONIZATION STRATEGY FOR THE SYNTHESIS OF ERYTHROMYCIN ANTIBIOTICS [J].

MARTIN, SF ;

YAMASHITA, M .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1991, 113 (14) :5478-5480

[7] THERMOTROPIC PROPERTIES OF SYNTHETIC CHAIN-SUBSTITUTED PHOSPHATIDYLCHOLINES - EFFECT OF SUBSTITUENT SIZE, POLARITY, NUMBER, AND LOCATION ON MOLECULAR PACKING IN BILAYERS [J].

MENGER, FM ;

WOOD, MG ;

ZHOU, QZ ;

HOPKINS, HP ;

FUMERO, J .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1988, 110 (20) :6804-6810

[8] SYNTHETIC FLUX-PROMOTING COMPOUNDS - EXCEEDING THE ION-TRANSPORTING ABILITY OF GRAMICIDIN [J].

MENGER, FM ;

DAVIS, DS ;

PERSICHETTI, RA ;

LEE, JJ .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1990, 112 (06) :2451-2452

[9] MORE ON MOTIONAL STATE OF LIPID BILAYER MEMBRANES - INTERPRETATION OF ORDER PARAMETERS OBTAINED FROM NUCLEAR MAGNETIC-RESONANCE EXPERIMENTS [J].

PETERSEN, NO ;

CHAN, SI .

BIOCHEMISTRY, 1977, 16 (12) :2657-2667

[10] ARCHAEBACTERIAL LIPID MODELS - HIGHLY THERMOSTABLE MEMBRANES FROM 1,1'-(1,32-DOTRIACONTAMETHYLENE)-BIS(2-PHYTANYL-SN-GLYCERO-3-PHOSPHOCHOLINE) [J].

YAMAUCHI, K ;

SAKAMOTO, Y ;

MORIYA, A ;

YAMADA, K ;

HOSOKAWA, T ;

HIGUCHI, T ;

KINOSHITA, M .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1990, 112 (08) :3188-3191